Tuesday, January 17, 2006

 

Increasing Alzheimer

Increasing Alzheimer’s and primary brain tumors:The price of fluoridation?
George Glasser/Andreas Schuld
USEPA admits that no chronic toxicity safety testing has been done with the fluorosilicic acid used to fluoridate drinking water, (phosphate fertilizer production pollution scrubber liquor and other fluorosilicates).
On 10 May 1999, US Rep. Ken Calvert, US House Subcommittee on Energy and the Environment, wrote to the US Environmental Protection Agency. The response, dated 23 June 1999, was made by J. Charles Fox, USEPA Assistant Administrator, at EPA Headquarters. In answer to Question Two: "What chronic toxicity test data are there on sodium fluorosilicate? On hydrofluorosilicic acid. . . ?" Fox wrote: "In collecting the data for the fact sheet EPA was not able to identify chronic studies for these chemicals."
Aside from the much debated fluoride issue, there is a component of the product that might be as bioactive as fluorine. It does not appear on Material Safety Data Sheets (MSDS) or in any quality control specification sheets (contaminant analyses). However, the component is part and parcel of the empirical formula and the chemical name, Silicon/Silica. All US government agencies are aware of this inherent, possibly carcinogenic, component of fluorosilicates, but refuse to acknowledge it. OSHA requires that any product containing a hazardous substance exceeding 1.0 % of the product be labeled on the product, yet OSHA will not acknowledge that fluorosilicic acid or sodium fluorosilicate used to fluoridate drinking water contains any elemental silica.
One water treatment chemical contract quality control laboratory, Underwriter’s Laboratories, states that they are not obligated to report silica/silicon levels. The primary quality control laboratory contracted by USEPA, National Sanitation Foundation, will not respond to requests for information about the silica levels. The avoidance of acknowledging the presence of silica/silicon in the water fluoridation agents is, more than likely, due to the fact that the fluorosilicates would have to be reclassified to no less than Group 2 substances (probable carcinogens).
The reclassification would disrupt industry and put a halt to drinking water fluoridation. All drinking water fluoridation research papers would be worthless, and a whole new set of Federal regulations for occupational exposures would have to be drafted and implemented.
While the regulatory government agencies procrastinate and industry pressures them to ignore the silica/silicon content, scientific evidence is mounting against silica/silicon as research turns up more nasty little secrets:
  1. 1998: "Primary brain tumors are among the most deadly of all cancers, with a 1-year survival rate of 52%. RESULTS: In a bivariate analysis, a statistically significant association was observed between the presence of brain tumors and the concentrations of silicon (p = 0.01)." (J. Environ. Pathol. Toxicol. Oncol. 1998; 17(1):1-9).

  2. Thirty-three patients had Alzheimer-type dementia (ATD); 16 patients had other dementing illnesses; and 20 had no neurologic disease. There were seven cases of autopsy-proven Alzheimer’s disease (AD) and eight autopsy controls. We found elevated CSF silicon in 24% of ATD and 71 % of AD patients. We found no relationship between CSF aluminum, arsenic, lead, or manganese and ATD, AD, or other dementing illnesses." (Neurology 1983 Oct; 33(10):1350-3)
Although documented extensively in the European literature, the synergistic action of silica and fluoride have yet to receive attention. Many reports surfaced especially during the 1950’s detailing findings as to how illnesses occurred faster and were more pronounced when fluorides were combined with silica.
Biochemical knowledge has made rapid progress since the 1950s. The discovery of G proteins has led to much greater understanding of the implications in the above named diseases, so much that it has become possible to explain pathways and show how many cancers happen. Entire databases of mutated G protein receptors exist, implicated in many diseases. G proteins are the molecular "Off/On" switches involved in the control of a wide range of biological processes - protein synthesis, signal transduction pathways, cancer growth and differentiation. Thousands of studies show how AlF4- has been used to activate such G proteins and mutations in animal and human tissue. An even further increase in potentiation is to be expected by the addition of silica, which will act synergistically with such a compound.Online, the Pubmed site http://www.ncbi.nlm.nih.gov/entrez) offers more than seven thousand citations on silica/silicon. Cancerlet, http://cnetdb.nci.nih.gov/cancerlit.shtml, offers several hundred citations regarding the association between silica/silicon exposures and cancers (also See: Greatful Med. http://igm.nlm.nih.gov/cgi ).
The average person who drinks water fluoridated with fluorosilicates will ingest about 0.40 milligrams of molecular silicates per day. However, both the molecular fluorides and silicates are easily absorbed through the skin and are more effective as toxicants. Unobstructed, with no possibility of minerals from foodstuffs in the stomach and intestinal tract to bind them into insoluble complexes, they enter the blood stream and search out target organs. The average person may absorb more silicates and fluorides from bathing than from ingestion of fluoridated water.
While ancillary exposures are not considered in research studies regarding water fluoridation, there is a significant potential household buildup of both airborne silicates and fluorides. This can occur, over a period of time, from the mere reality of washing clothes, bedding and items such as curtains and furniture covers. Neither the submicroscopic fluorides nor the silicates turn into vapors and vanish. They will be readily caught in fabrics and released into the air at the slightest rustle.
Inhaling airborne fluorides or silicates is a more highly effective way of metabolizing these toxicants than through ingestion or even through skin absorption. When they meet lung tissues, the molecules are released into the blood stream in their search for target organs.
All research conducted on drinking water fluoridation is concerned only with direct oral ingestion, using USP grade sodium fluoride. Researchers do not consider the reality of multiple exposures to fluorides and silica/silicon such as via bathing (absorption through the skin) and continual household contamination (inhalation). Therefore, people in long-term fluoridated areas are subject to many additional sources of fluoride and silica/silicon exposure than people in non-fluoridated areas, who are nevertheless exposed, via dental products, processed food and air pollution.
Since no research has ever been carried out on the chronic effects of exposure to fluorosilicates, any claims on the safety or efficacy of these substances are specious. Several of the consequences of the absolute refusal of all responsible federal agencies to undertake or commission appropriate research are as follows:
Dementia and AD:
Dutch researchers [Elferink, 1988] found that asbestos acts synergistically with phosphate analogues on G protein activation, supplying biochemical evidence for the earlier reports from 1950. Of course, fluoride aluminum compounds are well established and most effective phosphate analogues. Their implication in AD has been reviewed in great detail. [Strunecka, 1999]
Primary Brain Tumors:
There are over 100 different types of brain tumors, making effective treatment very complicated.
Identical G protein mutations are identified in many cancers, and have all been implicated in known aluminum/silica/fluoride poisonings. The ras oncogene-related protein (p21) is involved in 40 percent of colon cancers, and 40 percent of all cancers found in ‘Asbestosis’ and ‘Silicosis’, including osteosarcoma. (Brandt-Rauf et al, 1992). One study found that ALL human goiter nodules from different patients contained areas where the epithelial cells were morphologically grossly altered and heavily loaded with p21ras.(Studer 1992).As aluminum, silica and fluoride exist in almost all water supplies - and compound effects are so clearly demonstrated in the biochemical literature - the continued recommendation by public health officials that any of these substances should be added to the public drinking water supplies as a "health benefit" reveals an alarming degree of ignorance among so-called "recognized expert authorities". Their insistence that "only" the fluorine ion is of any concern must rank as one of the greatest examples of scientific incompetence ever visited on millions of unsuspecting people. The need for the fluoridating agent and all its components to be submitted to rigorous safety testing to prove that it is safe for human consumption is now a matter of urgency and all promotion of fluoridation should be halted until such data is available for public scrutiny.* CA: A Cancer Journal for Clinicians. January/February 1999. Vol. 49, No. 1, p.23** Brain Tumors: A Comprehensive Text, edited by Robert Morantz and John Walsh. pp.553. Marcel Dekker, Inc. 1994.*** Central Brain Tumor Registry of the United States, 1997 Annual Report
**** Central brain Tumor Registry of the United States, 1996 Annual Report

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